People with cluster headache were found to have higher cortisol and lower melatonin levels compared to individuals without headache disorders.
Notes on verification
Confirmed by multiple independent peer-reviewed studies (Chazot 1984, Leone 1995, Waldenlind et al.) and a 2023 systematic review/meta-analysis in Neurology, though some individual studies show conflicting details.
Sources
- Migraine and Cluster Headaches are Linked to the Body's Internal ... (healthline.com)
- https://pubmed.ncbi.nlm.nih.gov/36990725/ (pubmed.ncbi.nlm.nih.gov)
- https://www.aan.com/PressRoom/Home/PressRelease/5067 (aan.com)
- https://journals.sagepub.com/doi/10.1046/j.1468-2982.1995.015003224.x (journals.sagepub.com)
- https://pubmed.ncbi.nlm.nih.gov/6518501/ (pubmed.ncbi.nlm.nih.gov)
- https://www.neurology.org/doi/10.1212/wnl.0000000000207240 (neurology.org)