Researchers from Mayo Clinic's Center for Individualized Medicine found that epithelioid trophoblastic tumor recurrently exhibits an abnormal fusion of two genes.
Notes on verification
Confirmed by peer-reviewed PLOS One publication (Oliver et al., 2021) and corroborated by Mayo Clinic's own press release, both describing the LPCAT1-TERT fusion in epithelioid trophoblastic tumors.
Sources
- Gene fusion discovery in ultrarare tumor highlights potential therapeutic target - Mayo Clinic News Network (newsnetwork.mayoclinic.org)
- https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0250518 (journals.plos.org)
- https://pmc.ncbi.nlm.nih.gov/articles/PMC8148365/ (pmc.ncbi.nlm.nih.gov)
- https://advancingthescience.mayo.edu/2021/06/29/gene-fusion-discovery-in-ultrarare-tumor-highlights-potential-therapeutic-target (advancingthescience.mayo.edu)