The National Institutes of Health Women's Health Initiative reported that menopausal hormone therapy started in women age 65 or older increased the risk of dementia.
Notes on verification
Well-corroborated by the WHIMS trial (NIH-funded ancillary to WHI), peer-reviewed publications in JAMA, and subsequent reviews. Multiple independent sources including PubMed-indexed literature confirm the specific age-65+ finding.
Sources
- Estrogen Patch in Newly Postmenopausal Women May Reduce ... (newsnetwork.mayoclinic.org)
- https://pubmed.ncbi.nlm.nih.gov/19932751/ (pubmed.ncbi.nlm.nih.gov)
- https://pubmed.ncbi.nlm.nih.gov/15721829/ (pubmed.ncbi.nlm.nih.gov)
- https://pmc.ncbi.nlm.nih.gov/articles/PMC10302215/ (pmc.ncbi.nlm.nih.gov)
- https://www.alzforum.org/news/research-news/dementia-risk-increases-least-those-who-start-hormone-therapy-late (alzforum.org)