Elizabeth Habermann, Ph.D., the Robert D. and Patricia E. Kern Deputy Director of Research at Mayo Clinic, is a member of the CDC's Board of Scientific Counselors of the National Center for Injury Prevention and Control and its Opioid Work Group.
Researcher Irina Conboy found that joining the circulatory systems of old and young mice improved the older animals' ability to heal from injury.
IBM Watson's Oncology Expert Advisor received a $62 million investment over five years, but an internal investigation by the University of Texas M. D. Anderson Cancer Center found it fell short of the medical 'gold standard.'
Towards the end of the 19th century, scientists discovered phenomena in both the macro and micro worlds that classical physics could not explain.
In a 2024 study by Di Francesco et al. analyzing 937 female genetically diverse outbred mice, all four tested dietary interventions significantly extended lifespan compared to ad libitum-fed controls.
Gail Halpern and Michael Marcus met in a first-year chemistry class at MIT, began dating as sophomores, and married two days after graduating from MIT in 1968.
Multiple countries sent scientific expeditions around the world to observe the 1874 transit of Venus.
In the Di Francesco et al. (2024) study of female mice, the lifespan-extension effect was largest with 40% chronic caloric restriction, followed in order by 20% chronic caloric restriction, 2-day intermittent fasting, and 1-day intermittent fasting.
According to Halena Gazelka, M.D., the COVID-19 pandemic indirectly caused a significant increase in opioid overdoses in the United States, primarily due to illicit-market drugs such as fentanyl rather than clinical overprescribing.
Willard Libby's radiocarbon dates matched the verified ages of the objects he tested, launching the radiocarbon-dating revolution.
Poppy Northcutt was hired in 1965 through NASA contractor TRW after graduating early from the University of Texas with a degree in mathematics.
The senolytic drug mixture used in the research combined dasatinib, which promotes death of cancer cells, and quercetin, an antioxidant found in apples and other foods.
Diuretics, certain antidepressants, iron supplements, diabetes, and pelvic floor disorders can contribute to constipation in addition to age-related changes in the large intestine.
People who lived to ages 95–112 developed cancer, heart disease, diabetes, osteoporosis, and stroke up to 24 years later than people with average lifespans.
Google researchers labeled gender categories in their smile-detection model as 'Gender 1' and 'Gender 2' specifically to reduce the risk of introducing unconscious societal bias.
Ruth Bourne was a veteran of Bletchley Park, the British codebreaking center during World War II.
Rapamycin extended lifespan in both male and female UM-HET3 mice, with females showing a greater benefit than males (Harrison et al., 2009; Miller et al., 2011, 2014).
A draft of the CDC's updated 2022 opioid guideline was reviewed by an independent federal advisory committee, four peer reviewers, and members of the public before being revised.
Charles Darwin popularized the concept of evolution, which contributed to advances in the field of paleontology.
The last widow of a Civil War veteran died in 2020: Helen Viola Jackson married 93-year-old James Bolin in 1936 when she was 17.
Among US young adults aged 18–34, chronic-condition prevalence increased from 52.5% in 2013 to 59.5% in 2023, and multiple chronic condition prevalence increased from 21.8% to 27.1% over the same period.
In human fat samples obtained directly from the operating room, senolytic drugs eliminated senescent cells within 48 hours.
The comment by Gilbert, King, Pettigrew, and Wilson was published in Science, volume 351, issue 6277, pages 1037a–1038a, in 2016.
On February 19, 2025, HHS issued guidance stating that the U.S. government would recognize only two sexes—male and female—defining sex as a person's 'immutable biological classification' as either male or female.
Across every intervention and control group in three separate mouse studies, the estimated rate of vitality decline was consistently lower than the rate of survival decline; for example, female mice on 40% caloric restriction had a mean vitality-decline rate of 0.00011 compared to a survival-decline rate of 0.00079.
The NIA Interventions Testing Program found that acarbose significantly extended lifespan in both sexes of UM-HET3 mice, but the effect was much greater in males than in females (Harrison et al., 2014).
People with XY chromosomes and androgen insensitivity syndrome, an intersex condition, can develop external sex characteristics typical of females.
In the Da Qing Diabetes Prevention Study, the lifestyle-intervention group had fewer cardiovascular disease deaths (hazard ratio 0.67, 95% CI 0.48–0.94; p=0.022) and fewer all-cause deaths (hazard ratio 0.74, 95% CI 0.61–0.89; p=0.0015) than the control group.
In a small (n=9) phase I open-label clinical trial, a 3-day oral course of dasatinib plus quercetin reduced senescent-cell markers in adipose tissue and skin of people with diabetic kidney disease.
In mice with natural aging equivalent to about 80 human years, an oral mixture of senolytic drugs extended lifespan by 36% compared to the norm for that type of mouse.